Pentamidine-d4 dihydrochloride is a deuterium-labeled derivative of Pentamidine dihydrochloride, known for its role as an antimicrobial agent. This compound targets DNA biosynthesis and exhibits inhibitory effects on Leishmania infantum with an IC50 of 2.5 μM. Additionally, it acts as a potent and selective inhibitor of protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL). Pentamidine-d4 dihydrochloride holds therapeutic potential for conditions such as Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia, while also demonstrating antitumor and antibacterial activities.
Pentamidine-d4 dihydrochloride is a deuterium-labeled derivative of Pentamidine dihydrochloride, known for its role as an antimicrobial agent. This compound targets DNA biosynthesis and exhibits inhibitory effects on Leishmania infantum with an IC50 of 2.5 μM. Additionally, it acts as a potent and selective inhibitor of protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL). Pentamidine-d4 dihydrochloride holds therapeutic potential for conditions such as Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia, while also demonstrating antitumor and antibacterial activities.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
