Peptide R analogue 10

Name: Peptide R analogue 10
Brand: Adooq Bioscience
SKU: A36724
Rating: 5 (288 reviews)

Catalog No.: A36724

CXCR4 Antagonist

Peptide R analogue 10 is a potent CXCR4 antagonist, demonstrating enhanced antagonistic activity, specificity, and plasma stability compared to its predecessor, Peptide R. This compound effectively inhibits CXCL12-mediated cell migration, ERK phosphorylation, and CXCR4 internalization. Peptide R analogue 10 is valuable for research applications involving CXCR4 overexpression in models of leukemia and colon cancer.

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Peptide R analogue 10 1998129-59-1 CXCR4 Antagonist

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Biological Activity

Description

Product Information

Catalog Num	A36724
Formula	C41H59N13O9S2
Molecular Weight	942.12
CAS Number	1998129-59-1
Sequence	AC-Arg-Ala-DCys-Arg-Phe-Phe-Cys (disulfide bridge:DCys3-Cys7)
Sequence shortening	AC-RA-DCys-RFFC (disulfide bridge:DCys3-Cys7)
SMILES	C([C@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@H](C(O)=O)CSSC[C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC(C)=O)=O)C)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1)C3=CC=CC=C3

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