Peretinoin

Catalog No.: A18229

Peretinoin

Peretinoin Chemical Structure

CAS NO. 81485-25-8

Peretinoin, also known as NIK-333 , orally available, acyclic retinoid with potential antineoplastic and chemopreventive activities. Peretinoin binds to and activates nuclear retinoic acid receptors (RAR), which in turn recruit coactivator proteins and promote, with other transcriptional complexes, the transcription of target genes. As a result, this agent may modulate the expression of genes involved in the regulation of cell proliferation, cell differentiation, and apoptosis of both normal and tumor cells.

Availability: In stock

Package Price Qty
5 mg
$220.00
10 mg
$380.00
50 mg
$920.00
100 mg
$1,400.00
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Biological Activity

Peretinoin, also known as NIK-333 , orally available, acyclic retinoid with potential antineoplastic and chemopreventive activities. Peretinoin binds to and activates nuclear retinoic acid receptors (RAR), which in turn recruit coactivator proteins and promote, with other transcriptional complexes, the transcription of target genes. As a result, this agent may modulate the expression of genes involved in the regulation of cell proliferation, cell differentiation, and apoptosis of both normal and tumor cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.06 mL 165.32 mL 330.63 mL
0.5 mM 6.61 mL 33.06 mL 66.13 mL
1 mM 3.31 mL 16.53 mL 33.06 mL
5 mM 0.66 mL 3.31 mL 6.61 mL

*The above data is based on the productmolecular weight 302.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18229
CAS No. 81485-25-8
Formula C20H30O2
M. Wt 302.45
Purity >98%
Synonyms Peretinoin; NIK333
SMILES C/C(C)=C/CC/C(C)=C/CC/C(C)=C/C=C/C(C)=C/C(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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