Fig. 1 · Structure
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Perhexiline maleate
CPT1/CPT2 Inhibitor
Perhexiline maleate is a selective inhibitor of Carnitine Palmitoyltransferase 1 (CPT1) and Carnitine Palmitoyltransferase 2 (CPT2), which significantly reduces fatty acid metabolism. This compound induces mitochondrial dysfunction and apoptosis in hepatic cells, demonstrating potential anti-tumor activity. Additionally, Perhexiline maleate's ability to cross the blood-brain barrier makes it relevant for research applications in oncology and cardiovascular diseases, including angina.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 6724-53-4 |
| Applications | CPT1/CPT2 Inhibitor |
| Formula | C23H39NO4 |
| Molecular Weight | 393.56 |
| SMILES | O=C(O)/C=C\C(O)=O.C1(CC(C2CCCCC2)C3CCCCC3)NCCCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.