Permethrin-d6

Catalog No.: A52905
Stable Isotope
Permethrin-d6 is a deuterium-labeled derivative of the insecticide and acaricide Permethrin, which targets mitochondrial complex I. This compound exhibits significant estrogenic and anti-estrogenic activities, demonstrating its potential in endocrine disruption studies. Additionally, Permethrin acts as a neurotoxin by prolonging sodium channel activation in neuronal membranes, and it has been shown to reduce bacterial infection resistance in the medaka fish model (Oryzias latipes). Its stable isotope labeling makes Permethrin-d6 suitable for environmental monitoring and metabolic studies in chemical research.
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50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPermethrin-d6 is a deuterium-labeled derivative of the insecticide and acaricide Permethrin, which targets mitochondrial complex I. This compound exhibits significant estrogenic and anti-estrogenic activities, demonstrating its potential in endocrine disruption studies. Additionally, Permethrin acts as a neurotoxin by prolonging sodium channel activation in neuronal membranes, and it has been shown to reduce bacterial infection resistance in the medaka fish model (Oryzias latipes). Its stable isotope labeling makes Permethrin-d6 suitable for environmental monitoring and metabolic studies in chemical research.
Product Information
Catalog NumA52905
FormulaC21H14D6Cl2O3
Molecular Weight397.32
CAS Number82523-59-9
SMILESC(=C(Cl)Cl)C1C(C(OCC2=CC(OC3=CC=CC=C3)=CC=C2)=O)C1(C([2H])([2H])[2H])C([2H])([2H])[2H]
SynonymsNRDC-143-d6
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