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Pertuzumab
Pertuzumab is a humanized IgG1 monoclonal antibody designed to inhibit HER2 dimerization. This targeted mechanism of action makes it particularly effective in the treatment of metastatic HER2-positive breast cancer. Pertuzumab binds specifically to the HER2 receptor, blocking its ability to form dimers and activate downstream signaling pathways that promote tumor growth and survival. This agent is utilized primarily in research focused on understanding and treating HER2-positive breast cancer.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 380610-27-5 |
| Molecular Weight | 145440 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.