PF-04634817

Catalog No.: A18659

CCR2 /CCR5 dual antagonist

PF-04634817

PF-04634817 Chemical Structure

CAS NO. 1228111-63-4

PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema.

Availability: In stock

Package Price Qty
1 mg
$70.00
5 mg
$210.00
10 mg
$380.00
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Biological Activity

PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.55 mL 97.73 mL 195.47 mL
0.5 mM 3.91 mL 19.55 mL 39.09 mL
1 mM 1.95 mL 9.77 mL 19.55 mL
5 mM 0.39 mL 1.95 mL 3.91 mL

*The above data is based on the productmolecular weight 511.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18659
Actions Antagonist
M. Wt 511.59
Formula C25H36F3N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1228111-63-4
Synonyms PF-04634817; PF 04634817; PF04634817; PF-4634817; PF 4634817; PF4634817.
SMILES O=C([[email protected]]1(C(C)C)C[[email protected]](N[[email protected]@H]2[[email protected]](OC)COCC2)CC1)N3[[email protected]](C4)([H])CN(C5=NC=NC(C(F)(F)F)=C5)[[email protected]]4([H])C3

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