PF-04880594

Catalog No.: A12739

RAF inhibitor

PF-04880594 Chemical Structure

CAS NO. 1111636-35-1

PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
25 mg
$1,200.00
50 mg
$2,000.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.36 mL 126.78 mL 253.56 mL
0.5 mM 5.07 mL 25.36 mL 50.71 mL
1 mM 2.54 mL 12.68 mL 25.36 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

*The above data is based on the productmolecular weight 394.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12739
Actions Inhibitor
M. Wt 394.38
Formula C19H16F2N8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1111636-35-1
Synonyms PF-04880594, PF04880594, PF 04880594
SMILES C1=CNC2=NC=C(C=C21)C3=NN(C=C3C4=NC(=NC=C4)NCCC#N)CC(F)F

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