PF-04957325

Catalog No.: A21246

PDE8 inhibitor

PF-04957325

PF-04957325 Chemical Structure

CAS NO. 1305115-80-3

PF-04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively.

Availability: In stock

Package Price Qty
1 mg
$162.00
5 mg
$486.00
10 mg
$828.00
50 mg
$2,484.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.98 mL 124.88 mL 249.76 mL
0.5 mM 5 mL 24.98 mL 49.95 mL
1 mM 2.5 mL 12.49 mL 24.98 mL
5 mM 0.5 mL 2.5 mL 5 mL

*The above data is based on the productmolecular weight 400.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21246
Actions Inhibitor
M. Wt 400.38
Formula C14H15F3N8OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1305115-80-3
SMILES NC1=C(N=NN2C[[email protected]]3CN(CC4=NC=CS4)CCO3)C2=NC(C(F)(F)F)=N1

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