PF-05139962 is a cyclic sulfone compound that acts as a potent inhibitor of the mTOR kinase. It demonstrates strong inhibitory activity with a Ki of 5 nM and IC50 values of 48 nM for phosphorylated S473 and 6 nM for phosphorylated S6, highlighting its high selectivity. This compound is valuable for research applications involving cell growth, metabolism, and cancer therapy, particularly in studies focused on mTOR signaling pathways.
PF-05139962 is a cyclic sulfone compound that acts as a potent inhibitor of the mTOR kinase. It demonstrates strong inhibitory activity with a Ki of 5 nM and IC50 values of 48 nM for phosphorylated S473 and 6 nM for phosphorylated S6, highlighting its high selectivity. This compound is valuable for research applications involving cell growth, metabolism, and cancer therapy, particularly in studies focused on mTOR signaling pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
