PF-05175157

Catalog No.: A21460

ACC inhibitor

PF-05175157

PF-05175157 Chemical Structure

CAS NO. 1301214-47-0

PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.

Availability: In stock

Package Price Qty
5 mg
$63.00
10 mg
$109.00
50 mg
$322.00
100 mg
$644.00
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Biological Activity

PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.66 mL 123.31 mL 246.62 mL
0.5 mM 4.93 mL 24.66 mL 49.32 mL
1 mM 2.47 mL 12.33 mL 24.66 mL
5 mM 0.49 mL 2.47 mL 4.93 mL

*The above data is based on the productmolecular weight 405.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21460
Actions Inhibitor
M. Wt 405.49
Formula C23H27N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1301214-47-0
Synonyms PF05175157, PF 05175157
SMILES O=C1CC2(CCN(C(C3=CC=C4C(NC(C)=N4)=C3)=O)CC2)CC5=C1N(C(C)C)N=C5

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