Biological Activity
PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.89 mL | 114.44 mL | 228.88 mL |
0.5 mM | 4.58 mL | 22.89 mL | 45.78 mL |
1 mM | 2.29 mL | 11.44 mL | 22.89 mL |
5 mM | 0.46 mL | 2.29 mL | 4.58 mL |
*The above data is based on the productmolecular weight 436.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A20052 |
---|---|
Actions | Inhibitor |
CAS No. | 1387633-03-5 |
Formula | C19H21ClN4O4S |
M. Wt | 436.91 |
Purity | >98% |
Synonyms | PF05241328, PF 05241328 |
SMILES | O=C(C1=CC2=C(N(C3=CC(Cl)=C(OCC(C)C)N=C3)N=C2C)C=C1)NS(=O)(C)=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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