Fig. 1 · Structure
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PF-06284674
Cat. No.
A77412
CAS
1434288-24-0
PKM2 Activator
PF-06284674 is a potent activator of PKM2, a key enzyme involved in cancer metabolism. This compound enhances the activity of PKM2, promoting metabolic switching and cellular proliferation. It is primarily utilized in cancer research, particularly studies focused on targeting metabolic pathways for therapeutic intervention.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1434288-24-0 |
| Applications | PKM2 Activator |
| Formula | C17H14N4O |
| Molecular Weight | 290.32 |
| Synonyms | PKM2 activator 1 |
| SMILES | O=C1C=C(CN2C3=CC=CC=C3N=C2)N=C4N1C(C)=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.