PF-06422913 is a potent and selective negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5). This compound exhibits significant biological activity in modulating glutamatergic signaling, making it valuable in the study of neuropsychiatric disorders. Its applications include investigating therapeutic strategies for conditions such as anxiety and schizophrenia, where mGluR5 activity is implicated.
PF-06422913 is a potent and selective negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5). This compound exhibits significant biological activity in modulating glutamatergic signaling, making it valuable in the study of neuropsychiatric disorders. Its applications include investigating therapeutic strategies for conditions such as anxiety and schizophrenia, where mGluR5 activity is implicated.
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