PF-06446846 hydrochloride

Name: PF-06446846 hydrochloride
Brand: Adooq Bioscience
SKU: A24457
Rating: 5 (288 reviews)

Catalog No.: A24457

PCSK9 inhibitor

PF-06446846 hydrochloride is an orally active and highly selective inhibitor of the translation of proprotein convertase subtilisin/kexin type 9 (PCSK9). It inhibits PCSK9 expression by inducing ribosomal stalling at approximately codon 34 during translation.

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PF-06446846 hydrochloride 1632250-50-0 PCSK9 inhibitor

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Grouped product items
Size	Price	Stock
5mg	$108.00	In stock
10mg	$186.00	In stock
50mg	$552.00	In stock
100mg	$1,080.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	PF-06446846 hydrochloride is an orally active and highly selective inhibitor of the translation of proprotein convertase subtilisin/kexin type 9 (PCSK9). It inhibits PCSK9 expression by inducing ribosomal stalling at approximately codon 34 during translation.

Product Information

Catalog Num	A24457
Formula	C22H21Cl2N7O
Molecular Weight	470.35
CAS Number	1632250-50-0
SMILES	O=C(N(C1=NC=CC=C1Cl)[C@H]2CNCCC2)C3=CC=C(N4N=NC5=CC=CN=C54)C=C3.[H]Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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