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Biological Activity
PF-06471553 is a potent, selective and orally available monoacylglycerol acyltransferase 3 (MGAT3) inhibitor, with an IC50 of 92 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.39 mL | 106.94 mL | 213.89 mL |
| 0.5 mM | 4.28 mL | 21.39 mL | 42.78 mL |
| 1 mM | 2.14 mL | 10.69 mL | 21.39 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.28 mL |
*The above data is based on the productmolecular weight 467.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12640 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1808094-07-6 |
| Formula | C23H25N5O4S |
| M. Wt | 467.54 |
| Purity | >98% |
| Synonyms | PF06471553, PF 06471553 |
| SMILES | O=S(C1=CC2=C(CN(C(CC3=CC=CC(OC)=C3)=O)C2)C=C1)(NC4=NN(C5CCC5)N=C4)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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