PF-06700841 P-Tosylate

Catalog No.: A21652

dual JAK1/TYK2 inhibitor

PF-06700841 P-Tosylate

PF-06700841 P-Tosylate Chemical Structure

CAS NO. 2140301-96-6

PF-06700841 P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $72.00

Special Price $57.60

10 mg

Regular Price: $124.00

Special Price $99.20

50 mg

Regular Price: $368.00

Special Price $294.40

100 mg

Regular Price: $736.00

Special Price $588.80

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Biological Activity

PF-06700841 P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.81 mL 89.03 mL 178.06 mL
0.5 mM 3.56 mL 17.81 mL 35.61 mL
1 mM 1.78 mL 8.9 mL 17.81 mL
5 mM 0.36 mL 1.78 mL 3.56 mL

*The above data is based on the productmolecular weight 561.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21652
Actions Inhibitor
CAS No. 2140301-96-6
Formula C25H29F2N7O4S
M. Wt 561.6
Purity >98%
Synonyms PF0670084, PF 0670084
SMILES O=C([[email protected]]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.O=S(C6=CC=C(C)C=C6)(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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