Documents & Downloads

PF-07059013

HbS Modulator

PF-07059013 is a potent noncovalent modulator of sickled hemoglobin (HbS), exhibiting high binding affinity to hemoglobin with nanomolar potency. This compound demonstrates significant partitioning into red blood cells, making it a valuable tool for research on sickle cell disease (SCD). It is particularly useful for studies investigating therapeutic strategies aimed at modulating hemoglobin properties in SCD.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	2435610-93-6
Applications	HbS Modulator
Formula	C₁₉H₁₆FN₅O₂
Molecular Weight	365.36
SMILES	NC1=NC(C=CC(F)=C2)=C2C=C1O[C@H](C3=C(N4C=CC=N4)C=CC(N3)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.