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PF-4778574

Catalog No.: A21157

AMPA receptor positive allosteric modulator

PF-4778574

PF-4778574 Chemical Structure

CAS NO. 1219633-99-4

PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.61 mL 128.03 mL 256.07 mL
0.5 mM 5.12 mL 25.61 mL 51.21 mL
1 mM 2.56 mL 12.8 mL 25.61 mL
5 mM 0.51 mL 2.56 mL 5.12 mL

*The above data is based on the productmolecular weight 390.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21157
Actions Modulator
CAS No. 1219633-99-4
Formula C19H22N2O3S2
M. Wt 390.52
Purity >98%
Synonyms PF4778574, PF 4778574
SMILES O=S(N[[email protected]@H](CCOC1)[[email protected]]1C(C=C2)=CC=C2C3=CC=C(C#N)S3)(C(C)C)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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