PF-4800567

Name: PF-4800567
Brand: Adooq Bioscience
SKU: A21381
Rating: 5 (288 reviews)

Catalog No.: A21381

Casein kinase 1ε inhibitor

PF-4800567 is a potent and selective inhibitor of casein kinase 1ε (CK1ε), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM).

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PF-4800567 1188296-52-7 Casein kinase 1ε inhibitor

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Grouped product items
Size	Price	Stock
5mg	$30.00	In stock
10mg	$50.00	In stock
25mg	$110.00	In stock
50mg	$200.00	In stock
100mg	$290.00	In stock
200mg	$425.00	In stock
*10mM 1mL in DMSO**	$35.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

PF-4800567 is a potent and selective inhibitor of casein kinase 1ε (CK1ε), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM).

Targets

Target	Value

Product Information

Catalog Num	A21381
Formula	C17H18ClN5O2
Molecular Weight	359.81
CAS Number	1188296-52-7
SMILES	NC1=C2C(N(C3CCOCC3)N=C2COC4=CC=CC(Cl)=C4)=NC=N1
Synonyms	PF 4800567, PF4800567
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	70 mg/mL (194.54 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.79 mL	138.96 mL	277.92 mL
0.5 mM	5.56 mL	27.79 mL	55.58 mL
1 mM	2.78 mL	13.9 mL	27.79 mL
5 mM	0.56 mL	2.78 mL	5.56 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂