PF-562271

Catalog No.: A11192
FAK inhibitor
PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.
Grouped product items
Size Price Stock Qty
1mg
$45.00
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5mg
$115.00
In stock
10mg
$155.00
In stock
25mg
$265.00
In stock
50mg
$390.00
In stock
100mg
$590.00
In stock
500mg
$1,245.00
In stock
10mM * 1mL in DMSO
$135.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

Adooq Products cited in reputable paper
Adooq's PF-562271 has been cited by 1 publications
  • Jiping Yue, .et al. , Nat Commun, 2016, 7: 11692 PMID: 27216888
  • Biological Activity
    Discription PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A11192
    Formula C21H20F3N7O3S
    Molecular Weight 507.49
    CAS Number 717907-75-0
    SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
    Synonyms PF562271
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 91 mg/mL (179.31 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.7 mL 98.52 mL 197.05 mL
    0.5 mM 3.94 mL 19.7 mL 39.41 mL
    1 mM 1.97 mL 9.85 mL 19.7 mL
    5 mM 0.39 mL 1.97 mL 3.94 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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