PF-562271

Catalog No.: A11192
FAK inhibitor
PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.
Grouped product items
Product Name Price Stock Qty
PF-562271 5mg
$120.00
In stock
PF-562271 10mg
$180.00
In stock
PF-562271 50mg
$450.00
In stock
PF-562271 100mg
$800.00
In stock
PF-562271 10mM * 1mL in DMSO
$181.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PF-562271 has been cited by 1 publications
  • Jiping Yue, .et al. , Nat Commun, 2016, 7: 11692 PMID: 27216888
  • Biological Activity
    Discription PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.
    Targets
    Target Value
    Product Information
    Catalog Num A11192
    Formula C21H20F3N7O3S
    Molecular Weight 507.49
    CAS Number 717907-75-0
    SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
    Synonyms PF562271
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 91 mg/mL (179.31 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.7 mL 98.52 mL 197.05 mL
    0.5 mM 3.94 mL 19.7 mL 39.41 mL
    1 mM 1.97 mL 9.85 mL 19.7 mL
    5 mM 0.39 mL 1.97 mL 3.94 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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