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Biological Activity
PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme??s active site serine nucleophile.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.95 mL | 144.74 mL | 289.49 mL |
| 0.5 mM | 5.79 mL | 28.95 mL | 57.9 mL |
| 1 mM | 2.89 mL | 14.47 mL | 28.95 mL |
| 5 mM | 0.58 mL | 2.89 mL | 5.79 mL |
*The above data is based on the productmolecular weight 345.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21293 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 959151-50-9 |
| Formula | C22H23N3O |
| M. Wt | 345.44 |
| Purity | >98% |
| SMILES | O=C(NC1=CC=CC=C1)N(CC2)CCC2CC3=CN=C4C(C=CC=C4)=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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