Fig. 1 · Structure

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PFM03

MRE11 Endonuclease Inhibitor

PFM03 is an MRE11 endonuclease inhibitor that plays a pivotal role in the regulation of DNA double-strand break repair through nonhomologous end-joining (NHEJ). This compound is essential for studying the mechanisms of genomic stability and the cellular response to DNA damage. Its application in research helps elucidate the functions of MRE11 in various biological contexts, including cancer research and the investigation of DNA repair pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1558598-48-3
Applications MRE11 Endonuclease Inhibitor
Formula C14H15NO2S2
Molecular Weight 293.40
SMILES
OC1=CC=C(/C=C2C(N(C(C)CC)C(S/2)=S)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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