Fig. 1 · Structure
Documents & Downloads
PH-HG-005-5
Drug-Linker Conjugate
PH-HG-005-5 is a versatile drug-linker conjugate derived from SN-38. This compound facilitates the conjugation with targeting peptides, enabling the synthesis of antibody-drug conjugates (ADCs). Its primary application lies in the development of ADCs for targeted cancer therapies, enhancing therapeutic efficacy by delivering cytotoxic agents directly to tumor cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2810895-93-1 |
| Applications | Drug-Linker Conjugate |
| Formula | C41H47N7O10 |
| Molecular Weight | 797.85 |
| SMILES | CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC(C=C1)=CC=C1COC(O[C@]2(C3=C(COC2=O)C(N4C(C(C(C4)=C(C5=C6)CC)=NC5=CC=C6O)=C3)=O)CC)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.