Fig. 1 · Structure
Documents & Downloads
PHA-543613 hydrochloride
α7 nAChR Agonist
PHA-543613 hydrochloride is a potent agonist of the α7 nicotinic acetylcholine receptor (nAChR) with demonstrated brain permeability. This compound selectively targets α3β4, α1β1γδ, α4β2, and 5-HT3 receptors. PHA-543613 hydrochloride has shown significant effects on sensory gating and memory in in vivo models of schizophrenia, making it valuable for research in neuropharmacology and psychopharmacology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1586767-92-1 |
| Applications | α7 nAChR Agonist |
| Formula | C15H18ClN3O2 |
| Molecular Weight | 307.78 |
| SMILES | O=C(C1=CC2=C(OC=C2)C=N1)N[C@H]3CN4CCC3CC4.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.