Fig. 1 · Structure

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PHD-1-IN-4

PHD-1 Inhibitor

PHD-1-IN-4 is a potent inhibitor of prolyl hydroxylase domain containing protein 1 (PHD-1), exhibiting an IC50 of 0.074 μM. This compound demonstrates the ability to penetrate the blood-brain barrier, making it a valuable tool for neurological research. It is primarily utilized in studies investigating hypoxia-inducible factors and their roles in cellular responses to oxygen levels, offering insights into various pathophysiological conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2009343-19-3
Applications PHD-1 Inhibitor
Formula C14H10N4
Molecular Weight 234.26
SMILES
N#CC=1C=CC(C2=CC=CC3=NC=NN32)=C(C1)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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