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PHD-IN-2

PHD Inhibitor

PHD-IN-2 is a potent inhibitor of prolyl hydroxylase domain (PHD) enzymes, exhibiting an IC50 of less than 5 nM. This compound effectively stimulates erythropoietin production in HEP3B cells with an EC50 of less than 2.5 μM. PHD-IN-2 is valuable for research in various fields, including cardiovascular, metabolic, hematological, pulmonary, and kidney disorders, as well as liver dysfunction, wound healing, and cancer studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2924182-42-1
Applications	PHD Inhibitor
Formula	C₂₆H₂₇N₇O₄
Molecular Weight	501.54
SMILES	N#CC1=NC=C(CNC(C2=NC=C3N=C(N4CC5(C4)CN(C5)C(OC(C)(C)C)=O)C=CC3=C2O)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.