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PHD2-IN-5

PHD2 Inhibitor

PHD2-IN-5 is a potent inhibitor of prolyl hydroxylase domain 2 (PHD2), demonstrating an IC50 of 0.82 μM. This compound is valuable for investigating the role of PHD2 in renal anemia, making it a useful tool in studies related to oxygen sensing and erythropoiesis. Its selective inhibition of PHD2 can aid in the development of therapeutic strategies targeting anemia-related disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1262131-72-5
Applications	PHD2 Inhibitor
Formula	C₉H₉ClN₄O₄
Molecular Weight	272.65
SMILES	OC1=C(C(NCC(O)=O)=O)C2=NC=NN2C=C1.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.