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PHD2-IN-6

PHD2 Inhibitor

PHD2-IN-6 is a selective inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) with an IC50 of 31.6 nM. This compound promotes erythropoietin (EPO) production, making it valuable for studies related to erythropoiesis and hypoxia signaling. PHD2-IN-6 is particularly relevant for research in inflammatory diseases, including inflammatory bowel disease (IBD) and rheumatoid arthritis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1193382-79-4
Applications	PHD2 Inhibitor
Formula	C₁₇H₁₁ClN₄O₄S
Molecular Weight	402.81
SMILES	O=C(C1=CN(C2=NC3=C(N2)C=C(S(=O)(C4=CC=CC=C4)=O)C(Cl)=C3)N=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.