(Phe2,Nle4)-ACTH (1-24) (human, bovine, rat)

Catalog No.: A61676
ACTH Fragment
(Phe2,Nle4)-ACTH (1-24) is a synthetic fragment of the adrenocorticotropic hormone (ACTH) that targets the melanocortin receptors. This analog exhibits biological activity relevant to the study of adrenal function and stress response mechanisms. It can be utilized in various research applications, including radiolabeling with I125 at Tyr23 to create a radiolabeled ligand for biochemical assays and receptor binding studies.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(Phe2,Nle4)-ACTH (1-24) is a synthetic fragment of the adrenocorticotropic hormone (ACTH) that targets the melanocortin receptors. This analog exhibits biological activity relevant to the study of adrenal function and stress response mechanisms. It can be utilized in various research applications, including radiolabeling with I125 at Tyr23 to create a radiolabeled ligand for biochemical assays and receptor binding studies.
Product Information
Catalog NumA61676
FormulaC137H212N40O30
Molecular Weight2899.40
CAS Number97773-00-7
SequenceSer-Phe-Ser-{Nle}-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro
Sequence shorteningSFS-{Nle}-EHFRWGKPVGKKRRPVKVYP
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