Biological Activity
Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65??6 and 50??10 nM, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.16 mL | 90.81 mL | 181.62 mL |
0.5 mM | 3.63 mL | 18.16 mL | 36.32 mL |
1 mM | 1.82 mL | 9.08 mL | 18.16 mL |
5 mM | 0.36 mL | 1.82 mL | 3.63 mL |
*The above data is based on the productmolecular weight 550.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21250 |
---|---|
M. Wt | 550.61 |
Formula | C34H26N6O2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 942936-75-6 |
SMILES | C[N+]1=C2C=CC=CC2=CC(NC(C3=CC=C4C=CC5=CC=C(C(NC6=C[N+](C)=C7C=CC=CC7=C6)=O)N=C5C4=N3)=O)=C1 |
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