Fig. 1 · Structure
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Phenoxybenzamine
Alpha-adrenoceptor Antagonist
Phenoxybenzamine is a nonselective, irreversible α-adrenoceptor antagonist with significant implications in hypertension research, particularly related to pheochromocytoma. This compound exhibits notable antitumor activity, making it valuable for studies addressing both cardiovascular conditions and cancer biology. Phenoxybenzamine is useful in elucidating the role of adrenergic signaling in various physiological and pathological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 59-96-1 |
| Applications | Alpha-adrenoceptor Antagonist |
| Formula | C18H22ClNO |
| Molecular Weight | 303.83 |
| SMILES | CC(N(CCCl)CC1=CC=CC=C1)COC2=CC=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.