Fig. 1 · Structure
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Phenyl-glutarimide 4'-oxyacetic acid
Protein Ligand
Phenyl-glutarimide 4'-oxyacetic acid is a carboxylic acid-functionalized ligand targeting proteins involved in PROTAC (Proteolysis Targeting Chimeras) pathways. This compound exhibits enhanced hydrolytic stability and efficacy when interacting with PROTACs, making it a valuable tool for researchers developing PROTAC deactivators. Its distinct binding properties facilitate investigations into protein degradation mechanisms and associated signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2782024-58-0 |
| Applications | Protein Ligand |
| Formula | C13H13NO5 |
| Molecular Weight | 263.25 |
| SMILES | O=C(COC1=CC=C(C2C(NC(CC2)=O)=O)C=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.