Fig. 1 · Structure

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(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin

VP V1R Antagonist

(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a selective antagonist of the vasopressin V1 receptor (VP V1R). This compound demonstrates a significant reduction in mean arterial pressure (MAP) in rat models, making it a valuable tool for studying cardiovascular regulation and the physiological roles of vasopressin. Its application in research may enhance understanding of hypertension and related disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 129520-65-6
Applications VP V1R Antagonist
Formula C54H76N14O11
Molecular Weight 1097.27
SMILES
CCOc1ccc(C[C@@H](NC(=O)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)cc1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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