Fig. 1 · Structure
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Phenylbiguanide hydrochloride
5-HT Receptor Agonist
Phenylbiguanide hydrochloride is a selective agonist for the 5-HT3 receptor, exhibiting an EC50 of 3.0 ± 0.1 μM. This compound is primarily utilized in pharmacological studies investigating serotonin neurotransmission and its role in various physiological processes. It serves as a valuable tool for assessing the functional responses of 5-HT3 receptors in neurological and gastrointestinal research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 55-57-2 |
| Applications | 5-HT Receptor Agonist |
| Formula | C8H12ClN5 |
| Molecular Weight | 213.67 |
| Synonyms | N-Phenylbiguanide hydrochloride; PBG hydrochloride; 1-Phenylbiguanide hydrochloride |
| SMILES | NC(NC(NC1=CC=CC=C1)=N)=N.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.