Fig. 1 · Structure

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Phenylpyropene B

ACAT Inhibitor

Phenylpyropene B is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with an IC50 value of 12.8 μM. This compound demonstrates significant biological activity by reducing cholesterol esterification, making it a valuable tool in studies related to lipid metabolism and cardiovascular disease. Phenylpyropene B can be utilized in research applications focusing on cholesterol homeostasis, atherosclerosis, and related metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 556013-83-3
Applications ACAT Inhibitor
Formula C30H36O7
Molecular Weight 508.60
SMILES
C[C@@]12[C@]3([H])[C@](OC4=C(C(OC(C5=CC=CC=C5)=C4)=O)C3)(CC[C@@]1([H])[C@@](C)([C@H](CC2)OC(C)=O)COC(C)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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