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Biological Activity
Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.7 mL | 98.51 mL | 197.03 mL |
| 0.5 mM | 3.94 mL | 19.7 mL | 39.41 mL |
| 1 mM | 1.97 mL | 9.85 mL | 19.7 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
*The above data is based on the productmolecular weight 507.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21739 |
|---|---|
| Actions | Antagonist |
| CAS No. | 1227301-51-0 |
| Formula | C24H44Cl2N4O3 |
| M. Wt | 507.54 |
| Purity | >98% |
| Synonyms | PhTx 74 dihydrochloride |
| SMILES | O=C(NCCCCCCCNCCCCN)[C@@H](NC(CCC)=O)CC1=CC=C(O)C=C1.[H]Cl.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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