Philanthotoxin 74 dihydrochloride

Catalog No.: A21739

AMPAR antagonist

Philanthotoxin 74 dihydrochloride

Philanthotoxin 74 dihydrochloride Chemical Structure

CAS NO. 1227301-51-0

Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $54.00

Special Price $43.20

5 mg

Regular Price: $162.00

Special Price $129.60

10 mg

Regular Price: $276.00

Special Price $220.80

50 mg

Regular Price: $828.00

Special Price $662.40

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Biological Activity

Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.7 mL 98.51 mL 197.03 mL
0.5 mM 3.94 mL 19.7 mL 39.41 mL
1 mM 1.97 mL 9.85 mL 19.7 mL
5 mM 0.39 mL 1.97 mL 3.94 mL

*The above data is based on the productmolecular weight 507.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21739
Actions Antagonist
CAS No. 1227301-51-0
Formula C24H44Cl2N4O3
M. Wt 507.54
Purity >98%
Synonyms PhTx 74 dihydrochloride
SMILES O=C(NCCCCCCCNCCCCN)[[email protected]@H](NC(CCC)=O)CC1=CC=C(O)C=C1.[H]Cl.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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