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Phlorizin (Phloridzin)

Catalog No.: A10724

SGLT1/SGLT2 inhibitor

Phlorizin (Phloridzin)

Phlorizin (Phloridzin) Chemical Structure

CAS NO. 60-81-1

Phlorizin is a competitive inhibitor of SGLT1 and SGLT2; this reduces renal glucose transport, lowering the amount of glucose in the blood.

Availability: In stock

Package Price Qty
500 mg
$40.00
1000 mg
$70.00
5000 mg
$280.00
10mM * 1mL in DMSO
$59.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Subramaniam M, .et al. Comparison of Intestinal Glucose Flux and Electrogenic Current Demonstrates Two Absorptive Pathways in Pig and One in Nile Tilapia and Rainbow Trout, Am J Physiol Regul Integr Comp Physiol, 2019, Nov 20 PMID: 31746628

Biological Activity

Phlorizin is a competitive inhibitor of SGLT1 and SGLT2; this reduces renal glucose transport, lowering the amount of glucose in the blood.
Targets
In vitro DMSO Warmed: 81 mg/mL (185.6 mM)
Water Insoluble
Ethanol Warmed: 8 mg/mL (18.33 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.91 mL 114.57 mL 229.15 mL
0.5 mM 4.58 mL 22.91 mL 45.83 mL
1 mM 2.29 mL 11.46 mL 22.91 mL
5 mM 0.46 mL 2.29 mL 4.58 mL

*The above data is based on the productmolecular weight 436.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10724
Actions Inhibitor
CAS No. 60-81-1
Formula C21H24O10
M. Wt 436.4
Purity >98%
Synonyms Phlorhizin, Phlorizoside
SMILES C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[[email protected]]3[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O3)CO)O)O)O)O)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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