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- Subramaniam M, .et al. Comparison of Intestinal Glucose Flux and Electrogenic Current Demonstrates Two Absorptive Pathways in Pig and One in Nile Tilapia and Rainbow Trout, Am J Physiol Regul Integr Comp Physiol, 2019, Nov 20 PMID: 31746628
Biological Activity
Phlorizin is a competitive inhibitor of SGLT1 and SGLT2; this reduces renal glucose transport, lowering the amount of glucose in the blood.
Targets
| In vitro | DMSO | Warmed: 81 mg/mL (185.6 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 8 mg/mL (18.33 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.91 mL | 114.57 mL | 229.15 mL |
| 0.5 mM | 4.58 mL | 22.91 mL | 45.83 mL |
| 1 mM | 2.29 mL | 11.46 mL | 22.91 mL |
| 5 mM | 0.46 mL | 2.29 mL | 4.58 mL |
*The above data is based on the productmolecular weight 436.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10724 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 60-81-1 |
| Formula | C21H24O10 |
| M. Wt | 436.4 |
| Purity | >98% |
| Synonyms | Phlorhizin, Phlorizoside |
| SMILES | C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[[email protected]]3[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O3)CO)O)O)O)O)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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