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Phortress, also known as NSC-710305 and 5F-DF-203-L-lysinamide, is a P450 CYP1A1-activated antitumor prodrug with antitumor activity. Phortress free base leads to DNA damage and cell cycle arrest.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.77 mL | 108.84 mL | 217.68 mL |
| 0.5 mM | 4.35 mL | 21.77 mL | 43.54 mL |
| 1 mM | 2.18 mL | 10.88 mL | 21.77 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.35 mL |
*The above data is based on the productmolecular weight 459.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18458 |
|---|---|
| CAS No. | 741241-36-1 |
| Formula | C20H25Cl2FN4OS |
| M. Wt | 459.4 |
| Purity | >98% |
| Synonyms | Phortress; NSC-710305; NSC-710305; NSC-710305; 5F-DF-203-L-lysinamide; 5FDF 203Llysinamide |
| SMILES | NCCCC[[email protected]](N)C(NC1=CC=C(C2=NC(C=C(F)C=C3)=C3S2)C=C1C)=O.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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