Fig. 1 · Structure
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Phosphodiesterase II, Bovine Spleen
Phosphodiesterase
Phosphodiesterase II, Bovine Spleen (EC 3.1.16.1) is an enzyme that hydrolyzes cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), key second messengers in cellular signaling. This phosphodiesterase is widely expressed in various tissues, including the adrenal medulla, brain, heart, platelets, macrophages, and endothelial cells, making it vital for the regulation of numerous intracellular processes. Its application in biochemical research enables the exploration of pathways involving cAMP and cGMP, contributing to the understanding of signal transduction mechanisms in health and disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 9068-54-6 |
| Applications | Phosphodiesterase |
| Synonyms | 3′-Exonuclease |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.