Fig. 1 · Structure
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PhosTAC5
PhosTAC
PhosTAC5 is a phosphorylation-targeting chimera (PhosTAC) designed to facilitate the dephosphorylation of key regulatory proteins, specifically PDCD4 and FOXO3a. This compound features a polymeric linker consisting of five PEG groups, enhancing its solubility and stability. PhosTAC5 is valuable for studies investigating protein phosphorylation dynamics and its implications in cellular signaling pathways and cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3064090-15-6 |
| Applications | PhosTAC |
| Formula | C54H79ClN2O15 |
| Molecular Weight | 1031.66 |
| SMILES | O=C(NCCOCCOCCOCCOCCOCCCCCCCl)COC1=CC=CC([C@H](OC([C@@H]2CCCCN2C([C@H](C3=CC(OC)=C(OC)C(OC)=C3)CC)=O)=O)CCC4=CC(OC)=C(OC)C=C4)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.