Fig. 1 · Structure

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Photo-lenalidomide-acid

PHOTACs

Photo-lenalidomide-acid is a photochemical agent designed for use in PHOTACs (photo-controllable PROTACs). This compound consists of an E3 ligase ligand linked to a photoswitch and a ligand specific to a protein of interest, allowing precise optical control of protein degradation. Its innovative mechanism facilitates targeted protein modulation in cellular studies and therapeutic applications, making it a valuable tool for researchers investigating protein dynamics.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 2363154-39-4
Applications PHOTACs
Formula C23H22N4O8
Molecular Weight 482.44
SMILES
COC(C=C1/N=N/C2=C3C(C(N(C4C(NC(CC4)=O)=O)C3)=O)=CC=C2)=C(C(OC)=C1)OCC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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