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PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, which inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.07 mL | 115.33 mL | 230.67 mL |
| 0.5 mM | 4.61 mL | 23.07 mL | 46.13 mL |
| 1 mM | 2.31 mL | 11.53 mL | 23.07 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.61 mL |
*The above data is based on the productmolecular weight 433.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18473 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1614225-93-2 |
| Formula | C24H23N3O3S |
| M. Wt | 433.52 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | PHT7.3 |
| SMILES | O=C1C2=C(C=CC=C2)C(CC3OCCCO3)=NN1CC4=NC(C5=CC=C(C)C=C5)=CS4 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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