PHTPP

Catalog No.: A17035
ERβ receptor antagonist
PHTPP is a pyrazolo[1,5-α]pyrimidine-based ligand that acts as a full antagonist of estrogen ERβ receptors with 36-fold selectivity over ERα.
Grouped product items
Product Name Price Stock Qty
PHTPP 5mg
Special Price $52.00 Regular Price $65.00
In stock
PHTPP 10mg
Special Price $80.00 Regular Price $100.00
In stock
PHTPP 50mg
Special Price $280.00 Regular Price $350.00
In stock
PHTPP 100mg
Special Price $500.00 Regular Price $625.00
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Biological Activity
Discription PHTPP is a pyrazolo[1,5-α]pyrimidine-based ligand that acts as a full antagonist of estrogen ERβ receptors with 36-fold selectivity over ERα.
Product Information
Catalog Num A17035
Formula C20H11F6N3O
Molecular Weight 423.3
CAS Number 805239-56-9
SMILES OC(C=C1)=CC=C1C(C(C2=CC=CC=C2)=N3)=C4N3C(C(F)(F)F)=CC(C(F)(F)F)=N4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 49 mg/mL (115.75 mM)
Water Insoluble
Ethanol 82 mg/mL (193.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.62 mL 118.12 mL 236.24 mL
0.5 mM 4.72 mL 23.62 mL 47.25 mL
1 mM 2.36 mL 11.81 mL 23.62 mL
5 mM 0.47 mL 2.36 mL 4.72 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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