Fig. 1 · Structure
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Phyllodulcin
Sweetener, Phosphodiesterase Inhibitor
Phyllodulcin is a non-selective phosphodiesterase inhibitor and a naturally occurring sweetener derived from Hydrangea macrophylla var. thunbergii. This compound demonstrates anti-allergic properties by inhibiting lymphocyte activation. Additionally, Phyllodulcin has potential applications in obesity research through its ability to modulate leptin levels, affect fat browning-related gene expression, and influence hypothalamic BDNF-TrkB signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 21499-23-0 |
| Applications | Sweetener, Phosphodiesterase Inhibitor |
| Formula | C16H14O5 |
| Molecular Weight | 286.28 |
| SMILES | COC1=C(C=C(C=C1)[C@H]2CC3=C(C(=CC=C3)O)C(=O)O2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.