Fig. 1 · Structure
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Physalin A
Anti-cancer Agent
Physalin A is a bioactive withanolide with prominent anti-cancer properties. It exhibits significant antitumor activity by inducing apoptosis, enhancing reactive oxygen species (ROS) production, and causing G2/M phase cell cycle arrest. Additionally, Physalin A demonstrates anti-inflammatory and antifibrotic effects, while also improving autophagy in models of disc degeneration. Its ability to elevate quinone reductase activity and boost the expression of detoxifying enzymes further underscores its potential in cancer research and therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 23027-91-0 |
| Applications | Anti-cancer Agent |
| Formula | C28H30O10 |
| Molecular Weight | 526.53 |
| SMILES | C[C@@]([C@@](OC1=O)([H])C2)(OC3=O)[C@@]([C@@]3(CC[C@@]([C@]45C)([H])[C@@]6([H])[C@@H](C=C4CC=CC5=O)O)O)(O[C@@]76O)[C@](C7=O)([H])[C@]2(C1=C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.