PI3K-IN-31 is a potent inhibitor of phosphoinositide 3-kinases (PI3K), displaying IC50 values of 3.7 nM for PI3Kα, 74 nM for PI3Kβ, 14.6 nM for PI3Kγ, and 9.9 nM for PI3Kδ. Its selective inhibition of these kinases correlates with significant anticancer activity, making it a valuable tool in cancer research. Applications for PI3K-IN-31 include studying the PI3K signaling pathway and evaluating its role in tumorigenesis and therapeutic resistance.
PI3K-IN-31 is a potent inhibitor of phosphoinositide 3-kinases (PI3K), displaying IC50 values of 3.7 nM for PI3Kα, 74 nM for PI3Kβ, 14.6 nM for PI3Kγ, and 9.9 nM for PI3Kδ. Its selective inhibition of these kinases correlates with significant anticancer activity, making it a valuable tool in cancer research. Applications for PI3K-IN-31 include studying the PI3K signaling pathway and evaluating its role in tumorigenesis and therapeutic resistance.
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