PI3Kα-IN-1 is a potent inhibitor of the phosphoinositide 3-kinase alpha (PI3Kα) with an IC50 value of less than 0.5 nM. Additionally, it exhibits inhibitory activity against mTOR with an IC50 of 104 nM. This compound is valuable for studying the PI3K/mTOR signaling pathway, which is implicated in various diseases, including cancer and metabolic disorders. Research applications include evaluating the effects of PI3Kα inhibition on cell proliferation, survival, and signaling.
PI3Kα-IN-1 is a potent inhibitor of the phosphoinositide 3-kinase alpha (PI3Kα) with an IC50 value of less than 0.5 nM. Additionally, it exhibits inhibitory activity against mTOR with an IC50 of 104 nM. This compound is valuable for studying the PI3K/mTOR signaling pathway, which is implicated in various diseases, including cancer and metabolic disorders. Research applications include evaluating the effects of PI3Kα inhibition on cell proliferation, survival, and signaling.
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