PI3Kδ-IN-23 is a highly selective inhibitor of the PI3Kδ isoform, exhibiting an exceptional binding affinity with an IC50 value of 0.27 nM. This compound forms covalent bonds with the Lys779 residue on PI3Kδ, effectively blocking its activity. Its potent inhibition profile makes PI3Kδ-IN-23 a valuable tool for cancer research, particularly in studies focused on therapeutic strategies targeting PI3K signaling pathways.
PI3Kδ-IN-23 is a highly selective inhibitor of the PI3Kδ isoform, exhibiting an exceptional binding affinity with an IC50 value of 0.27 nM. This compound forms covalent bonds with the Lys779 residue on PI3Kδ, effectively blocking its activity. Its potent inhibition profile makes PI3Kδ-IN-23 a valuable tool for cancer research, particularly in studies focused on therapeutic strategies targeting PI3K signaling pathways.
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