PI3Kδ-IN-26 is a selective and orally active inhibitor of the PI3Kδ isoform, exhibiting an IC50 of 14 nM. This compound has demonstrated significant efficacy in attenuating inflammatory responses in house dust mite-induced chronic asthma models in mice. Due to its potent anti-inflammatory properties, PI3Kδ-IN-26 is a valuable tool for research into inflammatory, autoimmune, and hyperproliferative diseases.
PI3Kδ-IN-26 is a selective and orally active inhibitor of the PI3Kδ isoform, exhibiting an IC50 of 14 nM. This compound has demonstrated significant efficacy in attenuating inflammatory responses in house dust mite-induced chronic asthma models in mice. Due to its potent anti-inflammatory properties, PI3Kδ-IN-26 is a valuable tool for research into inflammatory, autoimmune, and hyperproliferative diseases.
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